Alpha-pyrrolidinovalerophenone – also known as α-PVP, alpha PVP (A-PVP), gravel, flakka or niff – is one of a number of recreational drugs in the ‘bath salts’ (or cathinone ) family, so-called because they resemble bath salts and because they have sometimes been sold disguised as them.

Originally synthesized in the 1960s, alpha-PVP usually comes in a crystal form that can be smoked, snorted, injected or swallowed. The high can last for three to five hours, but many users report it can be subtle at first and slow to come on. This has caused some to ‘re-dose’ early and use more than they intended – with unpleasant results.

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α-PVP(full name is:α-Pyrrolidinopentiophenone) also known as alpha-pyrrolidinovalerophenone, A-PVP, alpha-PVP, O-2387, APVP,,PVP,β-ketone-prolintane, Prolintanone). it is a synthetic stimulant drug of the cathinone class developed in the 1960s sometimes called flakka or gravel.

α-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane,and it is often used as a recreational drug, and is considered a Schedule I drug under the Food and Drug Administration Safety and Innovation Act.

Pyrovalerone is an inhibitor of the transporters for certain monoamine neurotransmitters, including dopamine and norepinephrine, preventing their uptake.1,2 α-Pyrrolidinopentiophenone (hydrochloride) is an analog of pyrovalerone, lacking only the methyl group that is found on the phenyl moiety of pyrovalerone. Like pyrovalerone, this compound is expected to be a psychoactive stimulant. This product is intended for forensic applications.

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